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Genomatix gmbh
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Blue Heron Biotech
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Genomatix gmbh
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Image Search Results
Journal: Annals of neurology
Article Title: Fatal Encephalopathy with Wild-Type JC Virus and Ruxolitinib Therapy
doi: 10.1002/ana.25608
Figure Lengend Snippet: Expansion transcription factor (TF) binding sites in patient JC virus (JCV) strain due to noncoding region 12bp insertion. Comparison of TF binding site differences between JCV_MdAV and reference JCV_GH3 in the region of 12bp insertion sequence uses Genomatix and MatInspector analysis. (A) Left: Patient sequence JCV_MdAV. Right: Reference archetype GH_3 sequence; red boxes represent new TF binding sites found in JCV_MdAV, and green demonstrates retained TF binding sites present in both patient and reference sequence. (B) New (red, A, left) TF binding sites present in noncoding region between bp 2585 TCTTTACTTTTT and 2596 that map to the 12bp insertion in the patient JCV_MdAV sequence.
Article Snippet:
Techniques: Binding Assay, Virus, Comparison, Sequencing